Synthetic Lethal Genetic Interaction


[Up] [Top]

Documentation for package ‘SLGI’ version 1.52.0

Help Pages

Atong Systematic genetic analysis with ordered arrays of yeast deletion Tong et. al. (2004).
AtongFnDomain The functional domains shared by the tested pairs in Tong et al experiment.
AtongPair Data frame the pair of yeast gene tested in Tong et al. 2004.
Boeke2006 Incidence matrix of Synthetic Lethal interaction from the Boeke Lab
Boeke2006raw Incidence matrix of Synthetic Lethal interaction from the Boeke Lab
byComplex Evaluate protein co-membership within cellular organizational units
comemberIn Retrieve the biological complexes.
compare Compare observed data to expected in permutation models
compare-method Compare observed data to expected in permutation models
congruence Calculate congruence score between pairs of of genes sharing pattern of synthetic genetic interactions (Ye et al. (2005)).
createSquareMatrix Create a square matrix
domainDist Finds the number of gene sets for each shared domain
dSLAM dSLAM platform used for Synthetic Lethal screens in the Boeke Lab
dSLAM.GPL1444 dSLAM platform used for Synthetic Lethal screens in the Boeke Lab
essglist The list of yeast essential genes
getAlignStats Functions to do local alignment of two sequences using EMBOSS matcher
getInteraction Count genetic interactions within and between cellular organizational units
getSharedDomains Find domains shared by a given list of gene names.
getSharedInteraction Calculate the number of shared synthetic genetic interactions between pairs of genes.
getTestedPairs Find interacting and non-interacting tested pairs from an genetic interaction matrix.
getUniquePairs Find unique pairs from an genetic interaction matrix.
gi2005 Genetic Interaction Data (EMAP) from the yeast early secretory pathway
gi2005.metadata Genetic Interaction Data (EMAP) from the yeast early secretory pathway
gi2007 Synthetic Genetic Interaction data from Collins et al
gi2007.metadata Synthetic Genetic Interaction data from Collins et al
gi2Interactome Reduce genetic interactions matrix
hyperG Hypergeometric test
iSummary Summarize cellular organizational units sharing genetic interaction
modelSLGI Permutation model for assessing synthetic genetic interactions in cellular organizational units.
normInteraction Normalize a matrix of biological interactions
plot Graphical method to represent the result of the modelSLGI .
plot-method Graphical method to represent the result of the modelSLGI .
SDL The Association matrix for the synthetic dosage lethal screens in Yeast.
seqMatcherAlign Functions to do local alignment of two sequences using EMBOSS matcher
SGA Systematic genetic analysis with ordered arrays of yeast deletion.
SGAraw Systematic genetic analysis with ordered arrays of yeast deletion.
SGD.SL Interaction data from the Saccharomyces Genome Database
SGD.SynGrowthDefect Interaction data from the Saccharomyces Genome Database
SGD.SynRescue Interaction data from the Saccharomyces Genome Database
sharedBy Find the gene pairs that share a domain.
sharedInt List shared genetic interactions between genes
show-method A class for representing the result of the SLGI graph permutation model.
siResult-class A class for representing the result of the SLGI graph permutation model.
SLchr The Association matrix for the synthetic dosage lethal screens in Yeast.
test2Interact Summarize genetic interactions within or between cellular organizational units
TFmat Transcription Factor Binding Affinities
tong2004raw Systematic genetic analysis with ordered arrays of yeast deletion Tong et. al. (2004).
topInteraction Extract interacting biological complexes
twoWayTable Generate two-way table for genetic interaction data
withinComplex Search for protein co-membership within complexes.