GOENTREZID2GO {GO}R Documentation

Entrez Gene to Gene Ontology (GO) mapping

Description

This data set describes associations between Entrez Gene identifiers and GO identifiers as reported by NCBI. The format is an R environment mapping Entrez Gene identifiers to a list of GO identifiers that are associated with it. In addition to the GO identifier. the GO ontology category and the evidence code (the reason for the association) is given.

Details

Each Entrez Gene identifier is mapped to a list of lists. The names on the outer list are GO identifiers. Each inner list consists of three named elements: GOID, Ontology, and Evidence.

The GOID element matches the GO identifier named in the outer list and is included for convenience when processing the data using lapply.

The Ontology element indicates which of the three Gene Ontology categories this identifier belongs to. The categories are biological process (BP), cellular component (CC), and molecular function (MF).

The Evidence element contains a code indicating what kind of evidence supports the association of the GO identifier to the Entrez Gene identifier. The evidence codes in use include:

IMP - inferred from mutant phenotype

IGI - inferred from genetic interaction

IPI - inferred from physical interaction

ISS - inferred from sequence similarity

IDA - inferred from direct assay

IEP - inferred from expression pattern

IEA - inferred from electronic annotation

TAS - traceable author statement

NAS - non-traceable author statement

ND - no biological data available

IC - inferred by curator

Entrez Gene identifiers for which no GO associations exist are left out of the environment.

Mappings were based on data provided by:

Entrez Gene:ftp://ftp.ncbi.nlm.nih.gov/gene/DATA. Built: Source data downloaded from Entrez Gene on Mon Apr 7 09:09:28 2008

Package built: Mon Apr 7 09:09:39 2008

References

http://www.ncbi.nih.gov/entrez/query.fcgi?db=gene

Examples

library("GO")
## Select an Entrez Gene id
egId <- "10043"
egIdGoData <- GOENTREZID2GO[[egId]]

## Display GO identifiers associated with the Entrez Gene id
sapply(egIdGoData, function(x) x$GOID)

## The ontology categories of the GO identifiers
sapply(egIdGoData, function(x) x$Ontology)

## The evidence codes for the GO identifiers
sapply(egIdGoData, function(x) x$Evidence)

[Package GO version 2.2.0 Index]