lumiB {lumi} | R Documentation |
Background correction of Illumina data
lumiB(lumiBatch, method = c('forcePositive', 'none', 'bg.adjust'), ...)
lumiBatch |
a LumiBatch Object, which can be the return of lumiR |
method |
the background correction method, it can be any function with a LumiBatch Object as the first argument and return a LumiBatch Object |
... |
other parameters used by the user provided background correction method |
The default background correction method ('forcePositive') will force all expression values to be positive by adding an offset (minus minimum value plus one), it does nothing if all expression values are positive. 'none' does not but return the lumiBatch object. 'bg.adjust' method is based on the bg.adjust
function in affy package. User can also provide their own function with a LumiBatch Object as the first argument and return a LumiBatch Object with background corrected.
Thanks Kevin Coombes (M.D. Anderson Cancer Center) suggested adding this function.
return a LumiBatch Object with background corrected.
Pan Du, Kevin Coombes
## load example data data(example.lumi) ## Do the default background correction method lumi.B <- lumiB(example.lumi)