poe.em {metaArray} | R Documentation |
This function applies fit.em function to all rows of a gene expression data matrix.
poe.em(mat, cl = NULL, threshold=1e-05, every = 100)
mat |
Gene expression data matrix |
cl |
A vector of 0s and 1s. Use 1 for normal phenotype and 0 for non-normal phenotype. If left blank, all samples will be labeled as normal phenotype. Normal component of mixture is estimated using samples with normal phenotype only. POE for samples with non-normal phenotype will be calculated after EM algorithm finishes ML estimation. |
threshold |
Criterion of convergence in likelihood |
every |
Progress of estimation is reported at every integer mode of the value 'every' |
A data matrix of transformed expression will result.
Debashis Ghosh <ghoshd@umich.edu>, Hyungwon Choi <hwchoi@umich.edu>