poe.em {metaArray}R Documentation

Probability of Expression from mixture distribution for multiple genes.

Description

This function applies fit.em function to all rows of a gene expression data matrix.

Usage

  poe.em(mat, cl = NULL, threshold=1e-05, every = 100)

Arguments

mat Gene expression data matrix
cl A vector of 0s and 1s. Use 1 for normal phenotype and 0 for non-normal phenotype. If left blank, all samples will be labeled as normal phenotype. Normal component of mixture is estimated using samples with normal phenotype only. POE for samples with non-normal phenotype will be calculated after EM algorithm finishes ML estimation.
threshold Criterion of convergence in likelihood
every Progress of estimation is reported at every integer mode of the value 'every'

Value

A data matrix of transformed expression will result.

Author(s)

Debashis Ghosh <ghoshd@umich.edu>, Hyungwon Choi <hwchoi@umich.edu>

Examples






[Package metaArray version 1.4.4 Index]