vandeVijver {globaltest}R Documentation

A subset of the Breast cancer data from Rosetta Inpharmatics LLC and Netherlands Cancer Institute.

Description

An exprSet containing expression data of 100 breast cancer patients on 407 selected genes plus the following phenotype data.

SampleID
Sample ID given by NKI for 295 samples in cohort study (NEJM 347, 01999, 2002)
FirstSeriesID
Sample ID in first series given by NKI for 78 samples in our first study (Nature 415, p530, 2002)
Posnodes
Lymph node status from pathology report
EVENTmeta
Distant metastasis at any time during follow-up, 0 = no, 1 = yes
EVENTdeath
Death, 0 = no, 1 = yes
TIMEsurvival
Total survival interval in years between first date of treatment and last date of follow-up (if EVENTdeath = 0) or date of death (if EVENTdeath = 1)
TIMErecurrence
Disease free interval in years between first date of treatment and last date of follow-up (if all 'EVENTs' are 0) or date of first EVENT (if one ore more 'EVENTs' are 1, i.e., local recurrence, loco-regional recurrence, second primary tumor or distant metastasis)
TIMEmeta
Metastasis free interval in years between first date of treatment and date of diagnosis of distant metastasis (only if EVENTmeta = 1) (note that interval relates to metastasis at any time during follow-up and not just as first event)
ESR1
Estrogen receptor alpha expression measurement from microarray (0 = no, 1 = yes)
NIH
Patient characteristics according to NIH criteria, 1 = low risk, 0 = high risk
St Gallen
Patient characteristics according to St. Gallen criteria, 1 = low risk, 0 = intermediate/high risk

Usage

data(vandeVijver)

Format

An exprSet. See the Biobase package

References

M.J. van de Vijver, Y.D. He, L.J. van 't Veer, H. Dai, A.A.M. Hart, D.W. Voskuil, G.J. Schreiber, J.L. Peterse, C. Roberts, M.J. Marton, M. Parrish, D. Atsma, A. Witteveen, A. Glas, L. Delahaye, T. van der Velde, H. Bartelink, S. Rodenhuis, E.T. Rutgers, S.H. Friend, and R. Bernards (2002). A gene-expression signature as a predictor of survival in breast cancer. New England Journal of Medicine 347 (25), 1999–2009.

See Also

annotation.vandeVijver.


[Package globaltest version 4.2.0 Index]