Calculate and Visualize Synergy Scores for Drug Combinations

Documentation for package ‘synergyfinder’ version 2.2.1

.ExtendedScores	Make a smooth surface for scores
AddNoise	Add noise to response value
Bliss	Calculate Bliss synergy score
CalculateSynergy	Calculate the synergy scores for drug combinations
CorrectBaseLine	Base line correction
ExtractSingleDrug	Extract single drug response from matrix
FindModelType	Find the type of model used for fitting dose response data
FitDoseResponse	Fitting single drug dose-response model
HSA	Calculate HSA synergy score
ImputeNA	Impute missing value with nearest values
kriging	Kriging
Loewe	Calculate Loewe synergy score
mathews_screening_data	A high-throughput drug combination screening data
PlotDoseResponse	Visualize the drug combination dose-response data
PlotSynergy	Drug interaction landscape
ReshapeData	Pre-processe the response data for furhter calculation and plot
ZIP	Calculate Delta synergy score based on ZIP model