Tools for Testing Gene-Gene Interaction at the Gene Level


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Documentation for package ‘GeneGeneInteR’ version 1.13.0

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CCA.test CCA (Canonical-Correlation Analysis) based GGI analysis.
CLD.test CLD (Composite Linkage Desequilibrium) based GGI analysis.
data.SNP Multiple genes dataset
gates.test Gene-based Gene-Gene Interaction analysis by combining SNP-SNP interaction tests
GBIGM.test GBIGM (Gene-based information gain method) for GGI analysis.
gene.pair A case-control dataset with two genes
GGI Gene-Gene Interaction Analysis of a set of genes
importFile Imports SNPs information from pedfile, PLINK, VCF (4.0) file, or genotypes imputed by IMPUTE2.
imputeSnpMatrix Missing values handling for SnpMatrix object
KCCA.test KCCA (Kernel Canonical-Correlation Analysis) based GGI analysis.
minP.test Gene-based Gene-Gene Interaction analysis by combining SNP-SNP interaction tests
PCA.test PCA-based Gene-Gene Interaction analysis.
plot.GGInetwork Plot a Gene-Gene Interaction Study with an heatmap-like visualization
PLSPM.test PLSPM (Partial Least Squares Path Modelling Analysis) based Gene-Gene Interaction analysis.
print.GGItest Printing objects of class '"GGItest"'
selectSnps Selects SNPs in snpMatrix and associated info data.frame, outputs of importFile.
snpMatrixScour SNP filtering based on Minor Allele Frequency, Hardy-Weinberg Equilibrium and call rate
summary.GGInetwork Printing summaries class '"GGInetwork"' objects
summary.GGItest Printing summaries class '"GGItest"' objects
tProd.test Gene-based Gene-Gene Interaction analysis by combining SNP-SNP interaction tests
tTS.test Gene-based Gene-Gene Interaction analysis by combining SNP-SNP interaction tests